The Vertex Foundation

Expanding Our Corporate Giving Commitment

About the Vertex Foundation

The Vertex Foundation, a nonprofit 501(c)3 foundation, seeks to improve the lives of people with serious diseases and in its communities through education, innovation, and health programs. Established in 2017, the Foundation is a long-term source of charitable giving and is part of our 10-year corporate giving commitment of $500 million.

How We Give Back

Below are some examples of the types of programs the Foundation supports.

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From hands-on learning modules to a STEM-focused summer camp, the Foundation’s partnership with i2Learning enables science, technology, engineering, and math to come alive for middle school students. With $5 million in new funding from the Foundation, i2Learning – an innovative organization that teams up with schools and districts to foster STEM education – is projected to reach more than 75,000 students and 3,000 teachers in Massachusetts.


When natural disasters strike, they have a devastating effect on both the families and communities impacted. That’s why the Foundation supports leading nonprofit partners that provide health-related relief services in times of disaster. In 2018, we supported Direct Relief, AmeriCares, and the American Red Cross to provide on-the-ground assistance following hurricanes Florence and Michael and during the California wildfires.


The Foundation also supports a dollar-for-dollar matching gift program designed to extend the impact of employees’ donations to qualified nonprofit organizations. In just over a year, employees contributed to about 1,300 nonprofit organizations through this program.



As we focus on education, innovation, and health in communities, the Vertex Foundation is partnering with leading local and national organizations. For example, we have supported programs that are cultivating career opportunities, combating the opioid epidemic, helping kids in crisis, and raising awareness of STEM careers. Learn more about some of the organizations here:

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Beginning in 2019, the Foundation will accept unsolicited donation requests from 501(c)3 organizations with articulated charitable programs targeting a defined unmet need. All applications must align with the Foundation’s focus on education, innovation, and health. Click here to access the grant application and additional guidelines.


The Vertex Foundation has moved to a bi-annual grant cycle. For additional information about the new 2020 grant cycles and submitting an application, please click here


The Vertex Foundation, Inc. is a 501(c)3 charitable organization. It is a separate legal entity from Vertex Pharmaceuticals Incorporated with distinct legal restrictions.