KALYDECO® (ivacaftor) Tablets, ORKAMBI® (lumacaftor/ivacaftor) Tablets, SYMDEKO® (tezacaftor/ivacaftor and ivacaftor) Tablets and TRIKAFTA® (elexacaftor/tezacaftor/ivacaftor and ivacaftor) Tablets

KALYDECO® (ivacaftor) Tablets 

ORKAMBI® (lumacaftor/ivacaftor) Tablets 

SYMDEKO® (tezacaftor/ivacaftor and ivacaftor) Tablets 

TRIKAFTA® (elexacaftor/tezacaftor/ivacaftor and ivacaftor) Tablets

  • This list does not imply that the products on this chart are interchangeable or have the same efficacy or safety. Please refer to each product's FDA-approved label and indication for further information.
  • The prices listed below are Average Wholesale Prices ("AWP") as established and made available to the public by a third party publisher or as calculated from data made available to the public by a third party publisher. The price paid by consumers may be higher or lower than the prices listed below. Information about AWP of these drugs is being provided to Vermont prescribers pursuant to Vermont law, to give you information about the relative prices of marketed drugs and other drugs in the same therapeutic class.
  • The prices listed here do not necessarily reflect price per dosage, price per course of treatment or the cost effectiveness, of all the products listed. For simplicity, only the smallest package sizes available for each product are included.

Product Name



PKG Size



Marketed Products 


KALYDECO® Oral Tablet 150 MG

Vertex Pharmaceuticals Incorporated

51167-0200-01 56 EA $28,675.36 $512.06

ORKAMBI® Oral Tablet 100-125 MG

Vertex Pharmaceuticals Incorporated

51167-0700-02 112 EA $25,103.08 $224.13

ORKAMBI® Oral Tablet 200-125 MG

Vertex Pharmaceuticals Incorporated 

51167-0809-01 112 EA $25,103.08 $224.13

SYMDEKO® Oral Tablet Therapy Pack 50-75 & 75 MG

Vertex Pharmaceuticals Incorporated

51167-0113-01 56 EA $26,880.00 $480.00

SYMDEKO® Oral Tablet Therapy Pack 100-150 & 150 MG

Vertex Pharmaceuticals Incorporated

51167-0661-01 56 EA $26,880.00 $480.00

TRIKAFTA® Oral Tablet Therapy Pack 100-50-75 & 150 MG

Vertex Pharmaceuticals Incorporated

51167-0331-01 84 EA  $28,675.36 $341.37

Other Products


Medispan is the source of this information.

Disclosure effective date: October 23, 2020

© 2020 Vertex Pharmaceuticals Incorporated l VXR-US-20-1900145 (v10.0) l 10/2020