Help us transform lives


Join our team

At Vertex, the world’s most talented and passionate people come together to advance science and transform lives, and in return, we invest in them so they can grow and advance their own careers. 

If you’re ready to join us, browse open positions below. If you want to stay connected, click here to join our Talent Community.



More than a job

Vertex employees are supported along their professional journeys and have the opportunity to grow and thrive in an inclusive and equitable environment that rewards and recognizes the moments that matter. We want to support your career from the beginning and along every step of the way, and we offer career growth and development opportunities regardless of your role or experience level.

To achieve our best, most meaningful work and deliver on our promise to patients, we need to be our best selves. That’s why we also offer industry-leading benefits and compensation to support our employees, their loved ones and our communities. 


Explore our spaces 

Our science is state of the art — and so are our labs, manufacturing facilities and workspaces. Each research site and office is designed to be both environmentally and employee friendly.  


Headquarters outside of the U.S. (International HQ) 

London is home to our headquarters for our international operations. Our offices on the Paddington Central campus are close to many transportation hubs and a variety of restaurants and cafés. We offer commuting perks as well as gym memberships (all within a 10-minute walk). All employees have access to a shared rooftop terrace. 



San Diego 

Our R&D labs in San Diego are located north of downtown in La Jolla, on the Torrey Pines Mesa, with UC San Diego, the Scripps Research Institute and many other biotech companies and research institutes nearby. There’s ample outdoor space, and we’re close to Torrey Pines State Natural Reserve and La Jolla Shores — for those who want to take a break to surf, swim or go for a run through the park or along the beach. 

female scientist at fume hood in a Vertex lab




Global headquarters

Our labs, office and manufacturing center in Boston are in the Seaport District and close to many transportation hubs. We offer commuting perks, as well as an on-site café (with an outdoor terrace and views of the harbor) and gym. The Seaport is also home to the new Jeffrey Leiden Center for Cell and Genetic Therapies.