Charles A. Sanders, M.D.

Dr. Sanders is Chairman of our Board of Directors. Dr. Sanders is distinguished as one of the few executives who has chaired three different pharmaceutical companies.

Dr. Sanders has served as our director since 1996 and as our lead outside director since 2003. He retired in 1994 as Chief Executive Officer and in 1995 as Chairman of Glaxo Inc. From 1990 to 1995, he served as a member of the board of Glaxo plc. From 1981 to 1989, Dr. Sanders held a number of positions at Squibb Corporation, including that of Vice Chairman. Dr. Sanders has previously served on the boards of Merrill Lynch, Reynolds Metals Co., Morton International Inc., Fisher Scientific International and Biopure Corporation. He is also a director of Biodel, Inc. and Cephalon Corporation, the lead director for Genentech, Inc., and the Chairman of the Board of Directors of Icagen, Inc. Dr. Sanders had his undergraduate education at the University of Texas, and earned an M.D. from the University of Texas Southwestern Medical School.